Dr. S.M. Zakir Hossain – Endocrinologist & Diabetic Foot Expert, Khulna
Dr. S.M. Zakir Hossain is a Consultant of Diabetology and Endocrinology at City Heart Diagnostic and Consultation Center, Khulna, with over 28 years of distinguished clinical, metabolic, and hormonal management experience. As an eminent Endocrinologist and Diabetic Footcare Specialist, he provides expert care for severe endocrine conditions, including Addison disease, pheochromocytoma, primary hyperparathyroidism, hypopituitarism, and acromegaly. Patients seeking expert hormonal evaluation and diabetic care receive evidence-based treatments tailored to halt disease progression, manage acute metabolic flare-ups, and prevent diabetic amputations. His medical practice combines high-precision endocrine diagnostics with individualized, multi-system patient care plans.
Professional Biography
Dr. S.M. Zakir Hossain completed his MBBS degree from Dhaka, establishing a comprehensive clinical foundation in general medical sciences. He demonstrated a profound commitment to metabolic health by earning his Certificate Course in Diabetology (CCD) from BIRDEM, the apex diabetes institution in Bangladesh, and a CC-CD from the National Heart Foundation. To address the critical complications of chronic diabetes, he pursued highly specialized Diabetic Footcare Training at the prestigious Christian Medical College (CMC) in Vellore, India. Finding the best Diabetes and Hormone Specialist in Khulna leads patients to rely on his 28+ years of dedicated clinical expertise in saving limbs and managing life-threatening hormonal imbalances.
His primary clinical focus includes life-saving corticosteroid replacement for Addison disease, intensive blood pressure management for pheochromocytoma, specialized hormonal suppression for acromegaly, and comprehensive surgical and medical debridement for diabetic foot ulcers. His diagnostic framework incorporates advanced dynamic endocrine testing, comprehensive neurovascular foot assessments, continuous glucose profiling, and comprehensive risk stratification to formulate effective, long-term metabolic strategies.
At-a-Glance Profile Card
| Profile Field | Details |
| Full Name | Dr. S.M. Zakir Hossain |
| Primary Specialty | Endocrinology & Diabetology |
| Secondary Specialties | Diabetic Footcare & Rare Adrenal/Pituitary Disorders |
| Designation | Consultant, Diabetology |
| Workplace | City Heart Diagnostic and Consultation Center, Khulna |
| Total Experience | 28+ Years |
| Location | Khulna, Bangladesh |
Qualifications & Education
MBBS (Dhaka) – Bachelor of Medicine and Bachelor of Surgery
CCD (Diabetes, BIRDEM) – Certificate Course in Diabetology, BIRDEM
CC-CD – Certificate Course in Cardiovascular Disease, National Heart Foundation
Diabetic Footcare Training – Specialized training from CMC Vellore, India
Designation & Workplace
Designation: Consultant, Diabetology
Workplace: City Heart Diagnostic and Consultation Center, Khulna
Diseases Treated
Addison disease requires life-saving lifelong corticosteroid replacement.
Pheochromocytoma demands urgent alpha-blockade and surgical referral.
Primary hyperparathyroidism needs calcium monitoring and metabolic care.
Hypopituitarism requires comprehensive multi-hormone replacement therapy.
Acromegaly demands specialized diagnostic testing and growth hormone suppression.
Type 1 diabetes requires lifelong insulin therapy and intensive glucose monitoring.
Type 2 diabetes demands lifestyle modification, oral hypoglycemics, and insulin management.
Diabetic foot ulcers need urgent debridement, infection control, and offloading.
Charcot neuroarthropathy requires urgent foot immobilization and specialized footwear.
Diabetic neuropathy demands neuropathic pain management and strict sugar control.
Hashimoto thyroiditis needs vigilant monitoring and thyroid hormone replacement.
Graves' disease requires anti-thyroid medications or radioactive iodine.
Polycystic ovary syndrome (PCOS) requires hormonal balancing and metabolic care.
Dyslipidemia requires targeted statin therapy and cardiovascular risk reduction.
Obesity and metabolic syndrome demand comprehensive medical weight management.
Clinical Specialties & Treatment Areas
Rare Endocrine & Adrenal Disorders: Precision management for complex diseases involving adrenal insufficiency (Addison's) and dangerous hormone-secreting tumors (Pheochromocytoma, Acromegaly).
Advanced Diabetic Footcare: Specialized, limb-saving interventions for severe diabetic ulcers, neuropathy, and infections utilizing protocols acquired from CMC Vellore.
General Diabetology & Metabolic Care: Expert, long-term management of Type 1 and Type 2 diabetes, leveraging 28 years of clinical experience to prevent systemic complications.
Advanced Procedure Breakdown
Comprehensive Diabetic Foot Assessment & Care
Utilizing his specialized training from CMC Vellore, Dr. Hossain performs meticulous foot screenings. This includes testing protective sensation with a 10g monofilament, assessing peripheral blood flow using handheld Doppler ultrasound, performing sharp wound debridement for non-healing ulcers, and prescribing specialized offloading footwear to prevent amputations.
Dynamic Endocrine Testing
Hormonal diseases like pheochromocytoma and acromegaly cannot be diagnosed with a simple blood test. Dr. Hossain conducts dynamic testing, such as 24-hour urine fractionated metanephrines for adrenal tumors, or oral glucose suppression tests for growth hormone excess, ensuring an accurate diagnosis of complex pituitary and adrenal pathologies.
Intensive Glycemic & Cardiovascular Optimization
Combining his CCD from BIRDEM and CC-CD from the National Heart Foundation, Dr. Hossain provides a holistic approach to diabetes. He optimizes insulin and oral hypoglycemic regimens while aggressively managing concurrent hypertension and dyslipidemia to prevent heart attacks and strokes in diabetic patients.
Condition-Specific Deep Dives
Addison Disease (Primary Adrenal Insufficiency)
A rare, potentially life-threatening disorder where the adrenal glands (located above the kidneys) fail to produce enough cortisol and aldosterone. Patients experience profound fatigue, unexplained weight loss, low blood pressure, and darkening of the skin. It requires exact, daily replacement of these steroid hormones to prevent a fatal adrenal crisis.
Pheochromocytoma
A rare, usually non-cancerous tumor that develops in the center of the adrenal gland. It secretes massive, uncontrolled amounts of adrenaline and noradrenaline. This causes sudden, dangerous spikes in blood pressure, severe headaches, profuse sweating, and a racing heart. Immediate medical blockade of the hormones is required before the tumor can be surgically removed.
Acromegaly
A rare hormonal disorder that develops when the pituitary gland produces too much growth hormone during adulthood, almost always due to a benign tumor. Because the long bones have fused, adults do not grow taller; instead, their hands, feet, and facial features slowly enlarge. It causes severe joint pain, hypertension, and requires medical or surgical suppression of the pituitary gland.
The Doctor’s Clinical Approach
Dr. S.M. Zakir Hossain utilizes nearly three decades of profound clinical wisdom to approach highly complex, multi-system endocrine diseases. His philosophy emphasizes detailed metabolic profiling to definitively diagnose the root cause of hormonal imbalances, prioritizing limb-saving interventions in advanced diabetes, and educating patients on the critical importance of daily foot hygiene and medication adherence.
Specialized Risk Factors
Emergency Callout: Immediate emergency medical evaluation is required if an Addison's patient experiences sudden, profound weakness, vomiting, and a drastic drop in blood pressure (Adrenal Crisis), a diabetic patient develops a new, rapidly spreading red and swollen infection on their foot with a high fever (risk of gangrene), or a patient experiences a sudden, violently high spike in blood pressure with a pounding headache (Pheochromocytoma crisis).
Certifications & Professional Memberships
Member, Bangladesh Medical and Dental Council (BMDC)
Alumni, BIRDEM (Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders)
Alumni, National Heart Foundation
Specialized Training Alumni, CMC Vellore, India
Patient Visit Preparation Checklist
Bring all prior blood test reports (especially Fasting/2-hour post-meal sugars, HbA1c, comprehensive hormone panels) and any previous ultrasound or MRI reports of the abdomen or brain.
Crucial for Footcare: Wear easily removable shoes and socks, and do not apply heavy creams to your feet on the day of the appointment so the doctor can accurately assess the skin and wounds.
Maintain a complete list of current prescription medications, particularly any past use of oral steroids or blood pressure medications.
Keep a detailed symptom diary noting sudden spells of sweating, heart palpitations, or unexplained weight changes.
Last Modified: October 25, 2026